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Table 2 CLART results for 5,068 samples, by age, screening history, cytology, and HC2 results

From: HPV prevalence and genotype distribution in a population-based split-sample study of well-screened women using CLART HPV2 Human Papillomavirus genotype microarray system

 

Outcomes on CLART, N (%)

Any high-risk HPV genotype (%)a

Negative on high-risk HPV genotypes (%)b

Only low-risk HPV genotypes (%)a

Invalid (%)

Total (%)

Total

1,274 (25.1%)

3,782 (74.6%)

622 (12.3%)

12 (0.2%)

5,068 (100%)

Age (years)

     

16-22

99 (61.1%)

63 (38.9%)

20 (12.3%)

0 (0.0%)

162 (100%)

23-29

608 (39.6%)

926 (60.3%)

216 (14.1%)

1 (0.1%)

1,535 (100%)

30-39

345 (22.6%)

1,176 (77.1%)

171 (11.2%)

4 (0.3%)

1,525 (100%)

40-49

135 (13.6%)

851 (85.8%)

119 (12.0%)

6 (0.6%)

992 (100%)

50-59

54 (10.7%)

452 (89.2%)

55 (10.8%)

1 (0.2%)

507 (100%)

60-65

24 (10.3%)

210 (89.7%)

25 (10.7%)

0 (0.0%)

234 (100%)

>65

9 (8.0%)

104 (92.0%)

16 (14.2%)

0 (0.0%)

113 (100%)

Screening history

     

Primary samplec

1,024 (23.2%)

3,375 (76.5%)

528 (12.0%)

11 (0.2%)

4,410 (100%)

Follow-up sample

250 (38.0%)

407 (61.9%)

94 (14.3%)

1 (0.2%)

658 (100%)

Cytology

     

Normal

1,001 (21.4%)

3,658 (78.3%)

561 (12.0%)

12 (0.3%)

4,671 (100%)

ASCUS

72 (58.5%)

51 (41.5%)

18 (14.6%)

0 (0.0%)

123 (100%)

LSIL

103 (72.5%)

39 (27.5%)

35 (24.6%)

0 (0.0%)

142 (100%)

≥HSIL

97 (91.5%)

9 (8.5%)

5 (4.7%)

0 (0.0%)

106 (100%)

≥ASCUS

272 (73.3%)

99 (26.7%)

58 (15.6%)

0 (0.0%)

371 (100%)

Inadequate

1 (3.8%)

25 (96.2%)

3 (11.5%)

0 (0.0%)

26 (100%)

HC2 d

     

Positive

874 (84.4%)

160 (15.5%)

111 (10.7%)

1 (0.1%)

1,035 (100%)

Negative

399 (9.9%)

3,619 (89.8%)

510 (12.7%)

11 (0.3%)

4,029 (100%)

  1. Abbreviations: ASCUS atypical squamous cells of undetermined significance, HC2 Hybrid Capture 2 assay, HPV Human Papillomavirus, ≥HSIL high-grade intraepithelial lesions or worse, LSIL low-grade squamous intraepithelial lesions.
  2. aThirteen high-risk and probably high-risk genotypes, according to the classification reported by IARC [2].
  3. bNone of the 13 high-risk or probably high-risk genotypes detected.
  4. cPredominantly screening samples, including a small proportion of samples taken for indication.
  5. dFour samples were not tested with HC2.
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BMC Infectious Diseases

ISSN: 1471-2334

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