No indication for tissue tropism in urogenital and anorectal Chlamydia trachomatis infections using high-resolution multilocus sequence typing

Table 4 Characteristics of Chlamydia trachomatis infections among women with concurrent infections at multiple anatomic locations, by Chlamydia trachomatis MLST cluster

Variable	Cluster I		Cluster II		Cluster III		Cluster IV		Residual		P
	n = 121		n = 60		n = 99		n = 46		n = 108
ompA genovar											-
B	0	(0.0%)	0	(0.0%)	0	(0.0%)	0	(0.0%)	4	(3.7%)
D	0	(0.0%)	0	(0.0%)	19	(19.2%)	2	(4.3%)	18	(16.7%)
E	121	(100.0%)	60	(100.0%)	0	(0.0%)	1	(2.2%)	21	(19.4%)
F	0	(0.0%)	0	(0.0%)	74	(74.7%)	0	(0.0%)	10	(9.3%)
G	0	(0.0%)	0	(0.0%)	0	(0.0%)	0	(0.0%)	24	(22.2%)
H	0	(0.0%)	0	(0.0%)	0	(0.0%)	0	(0.0%)	9	(8.3%)
I	0	(0.0%)	0	(0.0%)	0	(0.0%)	34	(73.9%)	3	(2.8%)
J	0	(0.0%)	0	(0.0%)	6	(6.1%)	9	(19.6%)	12	(11.1%)
K	0	(0.0%)	0	(0.0%)	0	(0.0%)	0	(0.0%)	7	(6.5%)
Anatomic location of infection											0.968
Cervical	40	(33.1%)	21	(35.0%)	37	(37.4%)	13	(28.3%)	38	(35.2%)
Urethral	33	(27.3%)	17	(28.3%)	25	(25.3%)	13	(28.3%)	28	(25.9%)
Vaginal	13	(10.7%)	8	(13.3%)	9	(9.1%)	8	(17.4%)	13	(12.0%)
Anorectal	28	(23.1%)	13	(21.7%)	24	(24.2%)	12	(26.1%)	24	(22.2%)
Pharyngeal	7	(5.8%)	1	(1.7%)	4	(4.0%)	0	(0.0%)	5	(4.6%)
Discordant multiple infections^a											0.330^*
No	110	(90.9%)	51	(85.0%)	87	(87.9%)	40	(87.0%)	88	(81.5%)
Yes	11	(9.1%)	9	(15.0%)	12	(12.1%)	6	(13.0%)	20	(18.5%)

Abbreviation: P P-value.
^*GEE is used.
^aDiscordant multiple infections defined as: having ≥ 2 paired samples with sequence types that belonged to different clusters.

ISSN: 1471-2334