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Figure 5 | BMC Infectious Diseases

Figure 5

From: Automated image-based assay for evaluation of HIV neutralization and cell-to-cell fusion inhibition

Figure 5

Comparison of neutralization sensitivity (IC50) of manual and automated readout in 72 virus-plasma combinations, including eight with HIV-negative plasma (denoted with a big X and arrow). The manual and automated readouts were from separate experiments. Readouts that do not vary more than 2-fold are denoted with x. Differences within a 2-3-fold range are depicted with a ring, and remaining virus-plasma combinations where the variation was >3-fold between manual and automatic readouts is depicted with a triangle. Triangle points are generally above the diagonal line indicating higher sensitivity of the automated readout. Statistically significant correlation between automated and manual readout according to Spearman rank (p < 0.0001, r = 0.8104).

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