Skip to main content

Table 1 Baseline characteristics of study patients

From: Therapeutic drug monitoring of nevirapine in saliva in Uganda using high performance liquid chromatography and a low cost thin-layer chromatography technique

Characteristic

Total (n = 297)

Nevirapine plasma conc. ≥3.0 mg/L (n = 282)

Nevirapine plasma conc. <3.0 mg/L (n = 15)

Sex, female

201 (67.7)

192 (68.1)

9 (60.0)

Age (years)

39.1 (32.8-45.2)

39.2 (33.1-45.2)

33.3 (30.9-42.8)

Time on ART (months)

28.5 (25.8-33.5)

28.1 (25.9-32.6)

31.1 (24.4-41.2)

NRTI backbone

   

  zidovudine

235 (79.1)

223 (79.1)

12 (80.0)

  tenofovir

19 (6.4)

17 (6.0)

2 (13.3)

HIV-RNA >400 copies/mL*

21 (8.9)

18 (8.1)

3 (23.1)

30-day adherence

   

  100%

260 (91.6)

248 (91.9)

12 (85.7)

  95- < 100%

19 (6.7)

18 (6.7)

1 (7.1)

  <95%

5 (1.8)

4 (1.5)

1 (7.1)

3-day adherence (any pills missed)

9 (3.3)

6 (2.3)

3 (20.0)

CD4 cell count (cells/mm3)

363 (265–509)

385 (269.5-511)

299 (211–354)

  1. Baseline characteristics stratified by patients with therapeutic (≥3.0 mg/l) or subtherapeutic (<3.0 mg/L) nevirapine plasma concentrations.
  2. Values in brackets are n (%) for categorical variables and median (interquartile range, IQR) for continuous variables. * HIV-RNA results from 235 patients were available.