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Table 1 Baseline characteristics of study participants

From: Evaluating the utility of early laboratory monitoring of antiretroviral-induced haematological and hepatic toxicity in HIV-infected persons in Cameroon

Characteristics

Number (%)

Characteristics

Number (%)

Gender

 

Absolute leucocyte count (/μl)

 

Female

105 (68.2)

  

Male

49 (31.8)

<4000

36 (27.1)

Total

154 (100)

≥4000

97 (72.9)

  

Total

133 (100)

Age group (years)

 

Absolute platelet count (/μl)

 

<30

19 (12.5)

  

30-49

93 (61.2)

<150000

19 (13.9)

≥50

40 (26.3)

≥150000

118 (86.1)

Total

152 (100)

Total

137 (100)

Marital status

 

Fasting blood sugar (mg/dl)

 

Single

47 (32.2)

  

Married

73 (50.0)

<126

130 (94.2)

Divorced

4 (2.7)

≥126

8 (5.8)

Widowed

22 (15.1)

Total

138 (100)

Total

146 (100)

  

Education level

 

NRTI-based regimen

 

None

8 (7.8)

AZT-based

79 (53.4)

Primary

33 (32.4)

D4T-based

2 (1.3)

Secondary

57 (55.9)

ABC-based

1 (0.7)

Higher

4 (3.9)

TDF-based

66 (44.6)

Total

102 (100)

Total

148 (100)

Alcohol use

 

NNRTI-based regimen

 

No

73 (47.4)

  

Yes

81 (52.6)

NVP-based

88 (59.5)

Total

154 (100)

EFV-based

60 (40.5)

  

Total

148 (100)

Smoking

 

Other medications

 

No

135 (87.7)

Tuberculosis

5 (3.25)

Yes

19 (12.3)

Haematinics

76 (49)

Total

154 (100)

Cotrimoxazole

133 (86.4)

  

Fluconazole

7 (4.5)

  

Traditional medicines

1 (0.7)

Pregnancy

 

CD4 count (cells/μl)

 

No

144 (93.5)

<350

134 (93.1)

Yes

10 (6.5)

≥350

10 (6.9)

Total

154 (100)

Total

144 (100)

ITN use

 

ALAT (U/L)

 

No

94 (61.0)

<45

136 (94.4)

Yes

60 (39.0)

≥45

8 (5.6)

Total

154 (100)

Total

144 (100)

WHO clinical stage

 

ASAT (U/L)

 

I

26 (19.0)

<42

132 (91.7)

II

21 (15.3)

≥42

12 (8.3)

III

83 (60.6)

Total

144 (100)

IV

7 (5.1)

  

Total

137 (100)

  

Weight (kg)

 

Haemoglobin (g/dl)

 

<60

62 (43.7)

<10

47 (32.4)

≥60

80 (56.3)

≥10

98 (67.6)

Total

142 (100)

Total

145 (100)

  1. ALAT = alanine aminotransferase, ASAT = aspartate aminotransferase, ITN = insecticide treated nets, NRTI = nucleotide reverse transcriptase inhibitor, NNRTI = non-nucleotide reverse transcriptase inhibitor, ABC = abacavir, D4T = stavudine, AZT = zidovudine, TDF = tenofovir, EFV = efavirenz, NVP = nevirapine, WHO = World Health Organisation.