Characteristics | Crude odd ratios (95% Confidence Interval) | p-value | Adjusted odd ratios (95% Confidence Interval) | p-value |
---|---|---|---|---|
Early liver enzyme elevation | ||||
NRTI-based regimens | ||||
AZT-based | 1 | 1 | ||
D4T-based | 18.3 (0.91-370.28) | 0.058 | 36.52 (1.44-924.38) | 0.029 |
ABC-based | 1 | 1 | ||
TDF-based | 1.83 (0.42-8.07) | 0.423 | 3.43 (0.61-19.21) | 0.160 |
Fasting blood sugar (mg/dl) | ||||
<126 | 1 | 1 | ||
≥126 | 6.40 (1.02-40.12) | 0.047 | 6.26 (1.00-39.30) | 0.50 |
Early anaemia | ||||
Baseline haemoglobin (g/dl) | ||||
≥10 | 1 | 1 | ||
<10 | 25.6 (8.61-76.17) | <0.0001 | 60.08 (13.36-270.20) | <0.0001 |
Body weight (kg) | ||||
<60 | 1 | 1 | ||
≥60 | 0.32 (0.12-0.88) | 0.027 | 0.28 (0.09-0.83) | 0.022 |
Use of ITN | ||||
No | 1 | 1 | ||
Yes | 4.41 (1.43-13.64) | 0.010 | 4.60 (1.35-15.71) | 0.015 |
NRTI-based regimens | ||||
AZT-based | 1 | 1 | ||
D4T-based | 1 | 1 | ||
ABC-based | 1 | 1 | 0.252 | |
TDF-based | 3.38 (1.56-7.32) | 0.002 | 2.01 (0.61-6.64) | |
Use of haematinics | ||||
No | 1 | 1 | ||
Yes | 3.74 (1.75-8.00) | 0.001 | 1.06 (0.32-3.49) | 0.921 |
Marital status | ||||
Single | 1 | 1 | ||
Married | 0.43 (0.18-0.99) | 0.049 | 0.54 (0.14-2.01) | 0.357 |
Divorced | 1 | 1 | ||
Widowed | 0.47 (0.15-1.53) | 0.212 | 0.81 (0.15-4.42) | 0.804 |