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Table 3 Cytokine production of splenocytes induced by STAg

From: Evaluation of immuno-efficacy of a novel DNA vaccine encoding Toxoplasma gondiirhoptry protein 38 (TgROP38) against chronic toxoplasmosis in a murine model

Groups

Cytokine production

IFN-γ

IL-2

IL-4

IL-10

Blank control

47.3 ± 16.6

12.7 ± 8.0

11.6 ± 9.5

477.3 ± 87.5

pVAX I

34.9 ± 11.2

12.4 ± 11.8

12.1 ± 3.4

322.5 ± 179.2

PBS

36.4 ± 4.8

11.3 ± 6.0

13.3 ± 1.8

356.1 ± 175.3

pVAX-ROP38

575.2 ± 123.0***

195.3 ± 28.4*

< 5

48.7 ± 24.3***

  1. STAg soluble tachyzoite antigens.
  2. Data are presented as the mean ± SD (n = 3).
  3. *represents statistically significant difference (P < 0.05).
  4. ***represents statistically highly significant difference (P < 0.01).