Table 2 Immune responses to pneumococcal polysaccharides at one month post-primary vaccination (primary ATP immunogenicity cohort): 22F-ELISA
| Â | Clin group | Com group | ||||
|---|---|---|---|---|---|---|
|  | N | % ≥0.2 μg/mL | GMC | N | % ≥0.2 μg/mL | GMC |
(95% CI) | (95% CI) | (95% CI) | (95% CI) | |||
Vaccine serotypes | Â | Â | Â | Â | Â | Â |
Serotype 1 | 219 | 100 | 2.67 | 218 | 100 | 2.46 |
(98.3 – 100) | (2.46 – 2.91) | (98.3 – 100) | (2.25 – 2.69) | |||
Serotype 4 | 219 | 100 | 3.95 | 218 | 100 | 3.14 |
(98.3 – 100) | (3.59 – 4.36) | (98.3 – 100) | (2.84 – 3.47) | |||
Serotype 5 | 219 | 99.5 | 4.34 | 218 | 100 | 3.59 |
(97.5 – 100) | (3.95 – 4.76) | (98.3 – 100) | (3.29 – 3.92) | |||
Serotype 6B | 219 | 96.3 | 1.31 | 218 | 93.6 | 1.23 |
(92.9 – 98.4) | (1.16 – 1.48) | (89.5 – 96.4) | (1.07 – 1.41) | |||
Serotype 7F | 218 | 100 | 3.10 | 217 | 100 | 3.20 |
(98.3 – 100) | (2.83 – 3.39) | (98.3 – 100) | (2.92 – 3.51) | |||
Serotype 9V | 219 | 100 | 3.34 | 218 | 100 | 3.14 |
(98.3 – 100) | (3.03 – 3.69) | (98.3 – 100) | (2.83 – 3.49) | |||
Serotype 14 | 219 | 99.5 | 5.13 | 218 | 100 | 4.74 |
(97.5 – 100) | (4.54 – 5.79) | (98.3 – 100) | (4.23 – 5.32) | |||
Serotype 18C | 219 | 100 | 5.00 | 218 | 99.5 | 5.15 |
(98.3 – 100) | (4.40 – 5.69) | (97.5 – 100) | (4.43 – 5.97) | |||
Serotype 19F | 219 | 99.5 | 6.69 | 218 | 99.5 | 6.96 |
(97.5 – 100) | (6.04 – 7.41) | (97.5 – 100) | (6.26 – 7.73) | |||
Serotype 23F | 219 | 98.2 | 1.98 | 218 | 97.2 | 1.68 |
(95.4 – 99.5) | (1.76 – 2.23) | (94.1 – 99.0) | (1.49 – 1.90) | |||
Cross-reactive serotypes | Â | Â | Â | Â | Â | Â |
Serotype 6A | 219 | 69.4 | 0.38 | 218 | 60.6 | 0.28 |
(62.8 – 75.4) | (0.32 – 0.45) | (53.7 – 67.1) | (0.23 – 0.33) | |||
Serotype 19A | 219 | 61.6 | 0.27 | 218 | 54.6 | 0.23 |
(54.9 – 68.1) | (0.23 – 0.31) | (47.7 – 61.3) | (0.20 – 0.27) | |||