Antibody | Target antigen | Protein function | Dilution |
---|---|---|---|
Secreted antigens | Â | Â | Â |
Anti-MPT32 | MPT32 (Apa, Rv1860) | Unknown (Could mediate bacterial attachment to host cells) | 1:500 |
Anti-MPT44 | MPT44 (Ag85A, fbpA, Rv3804c) | Involved in cell wall mycoloylation. Responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintaining cell wall integrity. | 1:100 |
Anti-MPT46 | MPT46 (Thioredoxin TrxC, Rv3914) | Participates in various redox reactions through the reversible oxidation of its active center dithiol, to a disulfide, & catalyzes dithiol-disulfide exchange reactions. | 1:500 |
Anti-MPT51 | MPT51 (Ag85D, fbpD, Rv3803c)/TB22.2 | Same as MPT44 | 1:500 |
Anti-MPT53 | MPT53 (DsbE, Rv2878c) | Unknown | 1:500 |
Anti-MPT59 | MPT59 (Ag85B, fbpB, Rv1886c) | Same as MPT44 | 1:100 |
Anti-MPT63 | MPT63 (Rv1926c) | Unknown | 1:500 |
Anti-MPT64 | MPT64 (Rv1980c) | Unknown (Suggested to inhibit apoptosis of infected cells) | 1:250 |
Somatic antigens | Â | Â | Â |
Anti-Mce1A | Mce1A (Rv0169) | Thought to be involved in cell invasion (entry and survival) | 1:2000 |
Anti-Hsp65 | Hsp65 (Ag82, GroEL2, Rv0440) | Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 1:500 |
Anti-MPT57 | MPT57 (GroES, Rv3418c) | Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 1:4000 |