| Hearing loss by type of diagnosis | ||
---|---|---|---|
 | No hearing loss | Hearing loss confirmed by audiogram | Clinical diagnosis of hearing loss |
Total patients, n (%) | 167 (38.2%) | 147 (33.6%) | 123 (28.2%) |
Baseline (initial amikacin dose) dose/kg(kilogram) | 17.0 (9.3 – 22.9) | 17.2 (15.4 – 18.9) | 17.2 (15.3 – 18.8) |
Mean daily dose of amikacin (dose/kg/month) | 16.2 (14.1 – 18.3) | 16.7 (15.3 – 18.9) | 16.6 (14.9 – 18.8) |
Number of patients in whom amikacin administration was changed from daily to 3 times per week | 51 (30.5%) | 131 (89.2%) | 115 (93.5%) |
Mean duration of daily amikacin treatment (days) | 164 (2 – 429) | 167 (105 – 210) | 175 (126 – 213) |
Mean duration of amikacin treatment given 3 times per week (days) | 67 (2 – 336) | 64 (41 – 105) | 68 (42 – 108) |
Overall duration of amikacin treatment (regardless of censoring; days) | 189 (2 – 528) | 195 (161 – 243) | 200 (175 – 249) |
Duration of amikacin treatment before censoring (days) | 189 (42 – 632) | 170 (104 – 212) | 167 (108 – 214) |