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Table 2 ALT elevation by HBsAg status in early adult life, comparing all HBsAg + cases vs a matched sample of twice as many HBsAg- controls 1986–90 births tested in 2007–08; analyses ignore vaccination status

From: Efficacy and effectiveness of infant vaccination against chronic hepatitis B in the Gambia Hepatitis Intervention Study (1986–90) and in the nationwide immunisation program

 

HBsAg + cases (n = 218)

HBsAg- controls (n = 472)

Odds ratio*

ALT category*

Below control mean

76 (34.9%)

288 (61.0%)

1

Mean to ULN

115 (52.8%)

173 (36.7%)

2.5

ALT 1-2x ULN

18 ( 8.3%)

10 ( 2.1%)

6.8

ALT >2x ULN

9 ( 4.1%)

1 ( 0.2%)

34.1

  1. p (trend) <0.0001.
  2. *In HBsAg- controls, mean ALT is 16 IU/L and upper limit of normal (ULN) is 35 IU/L.
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BMC Infectious Diseases

ISSN: 1471-2334

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