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Table 5 Univariate and multivariate hazard ratios for the association between male circumcision and clearance of genital HPV infection

From: Male circumcision and the incidence and clearance of genital human papillomavirus (HPV) infection in men: the HPV Infection in men (HIM) cohort study

 

Any HPV

Oncogenic HPV

Non-Oncogenic HPV

   

Univariatea

Multivariateb

  

Univariatea

Multivariatec

  

Univariatea

Multivariated

Circumcision

Inf./ Total

%

HR (95% CI)

AHR (95% CI)

Inf./ Total

%

HR (95% CI)

AHR (95% CI)

Inf./ Total

%

HR (95% CI)

AHR (95% CI)

No

4353/ 5981

72.8

1.00

1.00

1748/ 2266

77.1

1.00

1.00

2605/ 3715

70.1

1.00

1.00

Yes

2548/ 3398

75.0

0.92 (0.86 – 0.99)

0.95 (0.88 – 1.02)

1089/ 1410

77.2

0.86 (0.78 – 0.96)

0.90 (0.81 – 1.00)

1459/ 1988

73.4

0.97 (0.89 – 1.05)

0.98 (0.89 – 1.07)

Total

6901/ 9379

   

2837/ 3676

   

4064/ 5703

   
  1. aAdjusted for age and country;
  2. bCox model stratified by country and age, and adjusted for lifetime number of female sexual partners, recent number of male anal sex partners, smoking status, HPV status at baseline, and six-month visit compliance status;
  3. cCox model stratified by country and age, and adjusted for lifetime number of female sexual partners, lifetime number of male anal sex partners, HPV status at baseline, and six-month visit compliance status;
  4. dCox model stratified by country and age, and adjusted for recent number of female sexual partners, recent number of male anal sex partners, smoking status, HPV status at baseline, and six-month visit compliance status.
  5. NOTE: Unit of analysis: infections; Abbreviations: Inf., infections; HR, hazard ratio; CI, confidence interval; AHR, adjusted hazard ratio.