Table 1 Baseline characteristic of HIV-HBV/HCV study population at the date of stored plasma
Characteristics | N = 127 |
|---|---|
Gender, n(%) | |
Female | 45 (35.4%) |
Age, years | |
Median (range) | 34 (22, 56) |
Mode of HIV transmission, n (%) | |
Homosexual contacts | 17 (13.4%) |
Heterosexual contacts | 20 (15.7%) |
IDU | 87 (68.5%) |
Other/unknown | 3 (2.4%) |
Viral load, log10 copies/mL | |
Median (IQR) | 3.8 (3.0, 4.3) |
CD4 count, cells/mmc | |
Median (range) | 596 (208, 1303) |
Hepatitis co-infection, n (%) | |
HBV+/HCV- | 9 (7.1%) |
HCV+/HBV- | 118 (92.9%) |
Time from HIV seroconversion, years | |
Median (range) | 5 (0, 25) |
Calendar year of sample | |
Median (range) | 1998 (1997, 2008) |
Biomarkers | |
CD8CD38 + DR+, % (n = 120) | |
Median (IQR) | 45.0 (25.5, 54.9) |
IL-6, pg/ml (n = 279) | |
Median (IQR) | 1.1 (0.6, 2.1) |
LPS, pg/ml (n = 212) | |
Median (IQR) | 126.2 (75.0, 211.6) |
sCD14, mg/ml (n = 294) | |
Median (IQR) | 3.6 (2.0, 5.6) |
TNF-alfa, pg/ml (n = 286) | |
Median (IQR) | 2.3 (1.7, 3.4) |
ALT, IU/l (n = 360) | |
Median (IQR) | 40.0 (23.0, 63.0) |