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Table 2 Variables related with SVR at univariate and multivariate analysis (ITT).

From: Sustained virological response to peginterferon therapy in patients infected with HCV (genotypes 2 and 3), with or without HIV

 

Univariate Analysis

Multivariate Analysis

Variables

OR

(IC 95%)

pvalue

OR

(IC 95%)

pvalue

HCV-RNA >500.000 IU/ml

0.5 (0.3-0.7)

0.0009

0.39 (0.24-0.66)

0.0004

PegIFN alfa-2b vs alfa-2a

0.5 (0.3-0.9)

0.014

0.5 (0.27-0.93)

0.033

Stop PegIFN

0.1 (0.1-0-2)

<0.0001

0.19 (0.1-0.4)

<0.0001

Stop RBV

0.3 (0.2-0.5)

<0.0001

0.34 (0.17-0.69)

0.0026

PLT <130.000 cell/mm3

0.35 (0.2-0.6)

0.0004

0.45 (0.2-0.99)

0.048

Cirrhosis

0.6 (0.3-1.2)

0.15

1.37 (0.57-3.3)

0.47

Age >45 years

0.7 (0.45-1)

0.11

0.71 (0.4-1.26)

0.25

HIV infection

0.6 (0.4-1.1)

0.066

0.85 (0.32-2.23)

0.74

RBV reduction

1.5 (0.8-2.9)

0.25

  

PegIFN reduction

1.2 (0.6-2.6)

0.59

  

Gender (male vs female)

0.6 (0.4-0.9)

0.34

0.64 (0.36-1.14)

0.13

HCV genotype 2 vs 3

0.75 (0.48-1.16)

0.2

0.97 (0.5-1.8)

0.93

Variables

SVR no

SVR yes

p value

OR

(IC 95%)

p value

Weeks of treatment, mean (SD)

20.3 (15.4)

24.3 (12.2)

0.0006

1 (0.9-1.1)

0.22