Table 3 Effects of various inhibitors on S. marcescens W225 invasion of RT112 epithelial cells
From: Serratia marcescens internalization and replication in human bladder epithelial cells
Inhibitor | concentration | [%] invasion MOI 2 | [%] cytotoxicity MOI 2 | [%] invasion MOI 10 | [%] cytotoxicity MOI 10 |
|---|---|---|---|---|---|
None | - | 100 | 16.0 ± 2.4 | 100 | 90.0 ± 1.8 |
Chloroquine | 200 μg/ml | 98.0 ± 4.1 | 19.0 ± 1.8 | 97.2 ± 3.7 | 100 |
Cycloheximide | 10 μg/ml | 100 | 15.3 ± 2.6 | 102 ± 4.4 | 100 |
Cytochalasin D | 5 μg/ml | 54.0 ± 2.3 | 21.3 ± 2.6 | 62.0 ± 3.1 | 100 |
Dansylcadaverine | 500 μM | 100 | 18.2 ± 1.8 | 100 | 92.3 ± 5.4 |
Wortmannin | 25 μM | 55.0 ± 2.8 | 48.0 ± 4.4 | 3.0 ± 0.5 | 100 |
Colchizine | 0.2 μg/ml | 23.0 ± 2.1 | 7.2 ± 1.3 | 58.4 ± 6.3 | 46.8 ± 5.3 |
Paclitaxel | 1 μg/ml | 21.5 ± 3.2 | 11.7 ± 6.3 | 44.4 ± 5.8 | 40 ± 2.2 |