From: Vaccine candidates derived from a novel infectious cDNA clone of an American genotype dengue virus type 2
Replication in SCID-HuH-7 micea
Virus
No. of mice
Mean virus titer (log10PFU/ml ± SE)
DEN-2 Tonga/74
6
5.9 ± 0.3
rDEN-2
15
6.4 ± 0.2
rDEN2Δ30
22
5.2 ± 0.1
rDEN2Δ30-4995
28
4.6 ± 0.2