Field evaluation of a rapid immunochromatographic dipstick test for the diagnosis of cholera in a high-risk population

Table 2 Stratified analysis of the sensitivity and specificity of cholera dipstick test according to specimen (bulk stool or enriched rectal swab) and treatment (intravenous fluids or no intravenous fluids)

Dipstick test	Bacteriological culture		Total
	Positive	Negative
IV treatment – enriched rectal swab ^a
Positive	45	3	38
Negative	0	40	40
Total	45	43	78
IV treatment – bulk stool ^b
Positive	57	10	67
Negative	2	31	33
Total	59	41	100
No IV treatment – enriched rectal swab ^c
Positive	19	1	20
Negative	2	109	111
Total	21	110	131
No IV treatment – bulk stool ^d
Positive	10	13	23
Negative	3	46	49
Total	13	59	72

NOTE: IV = intravenous fluids were given.
^a Sensitivity was 100%; specificity was 93% (85–100); positive predictive value was 94%; and Kappa value was 0.93 (p < 0.05).
^b Sensitivity was 97% (92–100%); specificity was 76% (62–89%); positive predictive value was 85%;and Kappa value was 0.74 (p < 0.05).
^c Sensitivity was 91% (78–100%); specificity was 99% (97–100%); positive predictive value was 95%;and Kappa value was 0.91 (p < 0.05).
^d Sensitivity was 77% (54–100%); specificity was 78% (67–89%); positive predictive value was 43%;and Kappa value was 0.42 (p < 0.05).

ISSN: 1471-2334