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Table 1 Evolution of hematological detection in experimental leptospirosis in guinea pigs (n = 8 in each group), data are presented as mean ± SD. (*P < 0.05, compare with control)

From: Thrombocytopenia in the experimental leptospirosis of guinea pig is not related to disseminated intravascular coagulation

Characteristics Control 24 h after infection 48 h after infection 72 h after infection 96 h after infection
Platelet count (109/L) 564 ± 82 352 ± 40* 307 ± 50* 97 ± 35* 30 ± 14*
MPV (fL) 6.31 ± 0.19 6.53 ± 0.51 6.51 ± 0.18 7.04 ± 0.51* 8.09 ± 0.33*
11-DH-TXB2 (μg/L) 3.51 ± 0.55 5.12 ± 0.73* 4.85 ± 0.86* 5.31 ± 1.31* 7.46 ± 1.67*
TM (μg/L) 2.91 ± 0.30 3.40 ± 0.41* 5.63 ± 0.57* 6.62 ± 0.49* 6.87 ± 0.62*
TAT (μg/L) 3.66 ± 0.66 2.87 ± 1.01 3.27 ± 1.56 2.32 ± 0.77* 2.04 ± 0.25*
D-dimer (mg/L) 0.13 ± 0.01 0.19 ± 0.06* 0.24 ± 0.02* 0.27 ± 0.05* 0.19 ± 0.04*
FDPs (mg/L) 2.01 ± 0.08 1.99 ± 0.07 2.70 ± 0.53* 3.20 ± 0.43* 2.60 ± 0.56*