Clinical characteristics and initial management of patients with tuberculous pericarditis in the HIV era: the Investigation of the Management of Pericarditis in Africa (IMPI Africa) registry

Table 2 Clinical characteristics of the study population by clinical HIV status

	Clinical HIV disease	No clinical HIV disease	P
Number of patients	74 (40)	111 (60)
Age (median, range), years	36 (18–87)	32 (15–79)	0.14
Gender
Men	42 (40.8)	61 (59.2)
Women	32 (39.0)	50 (61.0)	0.81
Region
Eastern Cape, SA⁺	20 (34.5)	38 (65.5)
Western Cape, SA	11 (31.4)	24 (68.6)
Ibadan, Nigeria	6 (19.4)	25 (80.6)	0.0001
KwaZulu Natal, SA	11 (47.8)	12 (52.2)
Gauteng, SA	11 (52.4)	10 (47.6)
Yaoundé, Cameroon	15 (88.2)	2 (11.8)
Pericardial syndrome
Acute	1 (14.3)	6 (85.7)
Effusion	65 (44.2)	82 (55.8)
Effusive-constrictive	8 (28.6)	20 (71.4)
Constrictive	0 (0.0)	3 (100.0)	0.09
NYHA⁺⁺ Functional Class
I	8 (20.5)	31 (79.5)
II	27 (39.1)	42 (60.9)
III	20 (42.6)	26 (57.4)
IV	19 (63.3)	11 (36.7)	0.004
Haemodynamic instability**
Yes	24 (49.0)	25 (51.0)
No	50 (36.8)	86 (63.2)	0.13
Tamponade requiring centesis	17 (44.7)	21 (55.2)	0.97

Values are median (range) and absolute counts (percentages)
⁺SA, South Africa; ⁺⁺NYHA, New York Heart Association (I, No limitation of physical activity; II, Slight limitation of physical activity; III, Marked limitation of physical activity; and IV, Unable to carry out any physical activity without discomfort); **Pulse rate more than 100 bpm, Systolic blood pressure less than 100 mmHg and or tamponade requiring centesis.

ISSN: 1471-2334