Figure 1
From: Rapid diagnosis of experimental meningitis by bacterial heat production in cerebrospinal fluid
Heat power-time curves for S. pneumoniae (A), N. meningitidis (B) and L. monocytogenes (C). Black lines represent heat produced from 10-μl CSF samples drawn at 18 hours after infection from four rats per group and bacterial species. The corresponding mean (± SD) bacterial titer were 1.5 ± 0.6 × 108 cfu/ml for S. pneumoniae, 1.3 ± 0.3 × 106 cfu/ml for N. meningitidis and 3.5 ± 2.2 × 104 cfu/ml for L. monocytogenes. CSF from non-infected rats (controls) produced no heat. Grey lines represent serial 10-fold bacterial dilutions from 106 to 10-1 cfu/ml.