Skip to main content

Table 1 Relation between SLC11A1 and IL8R polymorphisms and tuberculosis in Chinese

From: Sex- and age-dependent association of SLC11A1polymorphisms with tuberculosis in Chinese: a case control study

Alleles/genotypes

TB patients

Control subjects

Odds ratio (95% CI)

Pvalue

Comparison of allele frequencies

   SLC1 a

      

(GT)9

478

(86%)

493

(87%)

1

 

Others

78

(14%)

71

(13%)

1.13 (0.80 – 1.60)

0.4780

   SLC6a/b b

      

G-TGTG

462

(83%)

497

(88%)

1

 

A- ----

94

(17%)

67

(12%)

1.51 (1.08 – 2.12)

0.0165 c

   IL8rb

      

C

370

(67%)

395

(70%)

1

 

T

186

(33%)

169

(30%)

1.18 (0.91 – 1.51)

0.2096

Comparison of genotype frequencies

   SLC1 a

      

(GT)9/(GT)9

204

(73%)

214

(76%)

1

 

(GT)9/others

70

 

65

   
  

(27%)

 

(24%)

1.14 (1.09 – 2.32)

0.4957

others/others

4

 

3

   

   SLC6a/b b

      

G-TGTG/G-TGTG

192

(69%)

220

(78%)

1

 

G-TGTG/A- ----

78

 

57

   
  

(31%)

 

(22%)

1.59 (1.09 – 2.32)

0.0163 c

A- ----/A- ----

8

 

5

   

   IL8rb

      

C/C

122

(44%)

135

(48%)

1

 

C/T

126

 

125

   
  

(56%)

 

(52%)

1.17 (0.84 – 1.64)

0.3438

T/T

30

 

22

   
  1. a "Others" represent the minor alleles (GT)10 and (GT)11 of the marker SLC1.
  2. b Markers SLC6a and SLC6b are in perfect LD and thus are analyzed as a single marker (SLC6a/b).
  3. c Significant even after correction of multiple testing based on false discovery rate at a level of 0.05. The adjusted cut-off P value is 0.0167 for six comparisons. For details, see additional file 1.