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Table 1 Criteria for appropriate vancomycin use according to the CDC criteria [4]

From: Analysis of vancomycin use and associated risk factors in a university teaching hospital: a prospective cohort study

Appropriate use
Serious infections caused by b-lactam-resistant Gram-positive microorganisms;
Infection caused by Gram-positive organisms in patients allergic to b-lactam antimicrobials;
Antibiotics treatment for colitis when there is a problem with metronidazole use or imminent life risk;
Surgical prophylaxis, with prosthesis implant, in institutions with high rates of oxacillin-resistant Gram-positive infections;
Neutropenics with extensive mucosite, infection related to venous catheters, previous prophylaxis with fluorquinolone, hypotension or sepsis.
Inappropriate use:
Routine surgical prophylaxis;
Febrile neutropenia that does not present isolation of oxacillin-resistant Gram-positive bacteria;
Treatment of a single blood culture for oxacillin-resistant Staphylococcus, coagulase-negative, if another culture collected simultaneously was sterile;
Empirical use, continuous, in patients whose cultures are negative for Gram-positive bacteria;
Presence of catheter and fever;
Decontamination of the gastrointestinal tract;
Prophylaxis for low birth weight infants;
Primary treatment of colitis by antibiotics;
Colonization by oxacillin-resistant Gram-positive bacteria;
Prophylaxis for patients in continuous peritoneal dialysis or hemodialysis;
Convenience treatment of infections by b-lactam-sensitive Gram-positive in hemodialysis patients;
Topical vancomycin use.