Figure 2

A-B. Significant decrease of IFN-gamma response to selected RD1 peptides over time in HIV ⁺ patients with active TB disease. A) Response to the sum of ESAT-6 and CFP-10 peptides and B) to the sum of ESAT-6 and CFP-10 proteins in terms of IFN-gamma spot-forming cells (SFCs) per million PBMC for each individual at the time of diagnosis and 6 months after therapy are reported. For 9/12 individuals data are reported also after 3 months of therapy. The p value denotes the difference between the responders in each group.