Variable | Entire Cohort (N = 416) | E. coli (N = 225)* | Klebsiella (N = 203)* |
---|---|---|---|
Age (mean in years, SD) | 55.3 ± 16.2 | 55.7 ± 16.2 | 54.9 ± 15.8 |
Male sex | 45.3% (188/415) | 49.1% (110/224) | 40.9% (83/203) |
Hospital-acquired Bacteremia†| 48.8% (203/416) | 39.1% (88/225) | 59.6% (121/203) |
Polymicrobial bacteremia | 21.4% (89/416) | 20.9% (47/225) | 26.6% (54/203) |
Appropriate empiric antimicrobial therapy | 73.3% (305/416) | 74.7% (168/225) | 70.9% (144/203) |
Admission to the ICU | 37% (154/416) | 36.0% (81/225) | 39.4% (80/203) |
Mechanical ventilation at admission | 9.6% (40/415) | 6.7% (15/224) | 13.3% (27/230) |
Mechanical ventilation at culture | 16.6% (69/415) | 14.7% (33/224) | 19.7% (40/203) |
Presence of central line at culture | 54.4% (225/414) | 43.5% (97/223) | 68.5% (139/203) |
APS before culture (mean, SD) | 22.7 ± 14.2 | 22.5 ± 14.6 | 22.9 ± 13.7 |
Chronic disease score (mean, SD) | 7.1 ± 3.9 | 6.9 ± 4.0 | 7.4 ± 3.7 |
Time at risk (median in days, IQR)††| 1.5 (0.1 to 10.0) | 0.4 (0.1 to 6.9) | 5.1 (0.2 to 13.3) |
Time to susceptibility (median in days, IQR)†††| 3.1 (2.6 to 3.9) | 3.1 (2.6 to 3.9) | 3.2 (2.6 to 4.1) |
Length of stay (median in days, IQR)††††| 7.0 (3.9 to 14.2) | 6.2 (3.7 to 12.1) | 8.7 (4.3 to 17.6) |
In-hospital mortality | 17.0% (71/416) | 17.8% (40/225) | 18.2% (37/203) |