Table 1 Demographic description of 140 admissions, overall and stratified by IVIG exposure

IVIG exposure (% of total cohort)

68 (48)

73 (52)

Gender

   Males

76 (54)

37 (55)

39 (53)

0.831

   Females

65 (46)

30 (45)

34 (47)

On HAART

54 (39)

21 (31)

33 (45)

0.092

On TB medication

39 (28)

17 (25)

22 (30)

0.496

Mortality

13 (9)

2 (3)

11 (15)

0.014

"Long" hospital stays

65 (46)

12 (18)

53 (73)

< 0.001

Age at admission (yrs)

   Median (IQR)

1.2 (0.5–2.3)

1.3 (0.6–2.5)

1.0 (0.4–2.1)

0.120

Weight at admission (kg)

   Median (IQR)

6.7 (4.7–9.5)

7.3 (5.0–10.9)

6.0 (4.6–8.3)

0.039

Temp. at admission (°C)

   Median (IQR)

37.3 (36.5–38.2)

37.4 (36.5–38.2)

37.3 (36.5–38.5)

0.812

Birth weight (kg)

   Mean (95% CI)

2.9 (2.8–3.0)

3.0 (2.8–3.2)

2.8 (2.7–3.0)

0.321

Hospital length of stay (days)

   Median (IQR)

15 (7–35)

8 (6–12)

30 (15–59)

< 0.001

Modified PRISM percentage

   Median (IQR)

11 (0–21)

6 (0–15)

14 (6–28)

0.004

Hemoglobin on admission

   Median (IQR)

9.1 (8.1–10.3)

9.3 (8.4–10.5)

8.7 (8.0–10.2)

0.202

Diagnosis

   Lower respiratory tract infection

94 (67)

50 (75)

44 (60)

0.062

   Bacterial sepsis

74 (53)

24 (36)

50 (68)

< 0.001

   Bacterial meningitis

4 (3)

2 (3)

2 (3)

0.931

   TB

40 (29)

16 (24)

24 (33)

0.239

   TB meningitis

2 (1)

1 (2)

1 (1)

0.951

   Gastroenteritis

54 (39)

21 (31)

33 (45)

0.092

   Urinary tract infection

15 (11)

4 (6)

11 (15)

0.082

   PEM

16 (11)

7 (10)

9 (12)

0.727

   Fungal sepsis

4 (3)

0 (0)

4 (5)

0.052

   Failure to thrive

29 (21)

8 (12)

21 (29)

0.014

Cultures

   Any positive blood culture

85 (61)

29 (43)

56 (77)

< 0.001

   Positive E. coli blood culture

4 (3)

2 (3)

2 (3)

0.931

   Positive S. pneumoniae blood culture

21 (15)

10 (15)

11 (15)

0.981

   Positive C. albicans urine culture

7 (5)

0 (0)

7 (10)

0.009

Received

   1st-line antibiotics

118 (84)

53 (79)

65 (89)

0.107

   2nd-line antibiotics

42 (30)

12 (18)

30 (41)

0.003

   3rd-line antibiotics

51 (36)

10 (15)

41 (56)

< 0.001

   4th-line antibiotics

44 (31)

5 (7)

39 (53)

< 0.001

   IV ampicillin

92 (66)

37 (55)

55 (75)

0.012

   IV cefotaxime

32 (23)

6 (9)

26 (36)

< 0.001

   IV vancomycin

21 (15)

2 (3)

19 (26)

< 0.001

   IV piperacillin/tazobactam

21 (15)

4 (6)

17 (23)

0.004

   IV fluconazole

14 (10)

0 (0)

14 (19)

< 0.001

   IV amphotericin

8 (6)

0 (0)

8 (11)

0.005