How is tenofovir dosing adjusted for a hemodialysis patient? Tenofovir should be dosed at 300 mg every 7 days or after a total of approximately 12 hours of hemodialysis. Dose should be given after hemodialysis session. |
Should sulfadiazine be used alone for toxoplasmosis prophylaxis? No. It should be used in conjunction with pyrimethamine and leucovorin. |
What are the electrolyte abnormalities associated with Amphotericin B? Decreased magnesium, decreased calcium, and decreased or increased potassium. |
Can nitazoxanide suspension be given safely to diabetic patients? Diabetics should be aware that the suspension contains 1.48 grams of sucrose per 5 mL. |
What three drugs have cases reporting increased levels when administered with Fluzone? Phenytoin, warfarin, and theophylline. |
What specific resistance profile has been documented in an HIV/HBV patient taking entecavir? M184V resistance substitution has occurred in the HIV strain. |
What is used to reconstitute ertapenem for intramuscular administration? 3.2 mL of 1% Lidocaine HCl injection (without epinephrine). |
What preservative does the Pneumovax pneumococcal vaccine contain? Phenol 0.25%. |
How does spinal fluid concentrations of amikacin compare to serum concentrations in infants? Spinal fluid levels in normal infants are approximately 10 to 20% of the serum concentrations and may reach 50% when the meninges are inflamed. |
What is the spectrum of activity of acyclovir? Herpes simplex virus types 1 (HSV-1), 2 (HSV-2), and varicella-zoster virus (VZV). |
Can metronidazole be given to pregnant patients with trichomoniasis? It is contraindicated during the 1st trimester of pregnancy due to lack of clinical evidence. |
Against what viruses have foscarnet and ganciclovir shown a synergistic effect both in vitro and in vivo? Cytomegalovirus and herpes simplex virus type 2. |
Why should willow bark be avoided 6 weeks after receiving Varivax? Because Reye's Syndrome has been reported following natural varicella infection. |