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Table 4 Diagnostic accuracy of serum PCT for the diagnosis of sepsis in critically ill patients with either primary or secondary BSI-related sepsis.

From: Impact of previous sepsis on the accuracy of procalcitonin for the early diagnosis of blood stream infection in critically ill patients

PCT cutoff value (ng/mL)

Sepsis type

Sensitivity (%)

Specificity (%)

Positive predictive value (%)

Negative predictive value (%)

PCT ≥ 0.25

Primary

98.3

47.8

90.5

84.6

 

Secondary

90.3

47.8

82.3

64.7

PCT ≥ 0.50

Primary

94.9

65.2

93.3

71.4

 

Secondary

83.9

65.2

86.7

60.0

PCT ≥ 1.00

Primary

89.7

73.9

94.6

58.6

 

Secondary

72.6

73.9

88.2

50.0

PCT ≥ 2.00

Primary

83.8

82.6

96.1

50.0

 

Secondary

58.1

82.6

90.0

42.2

  1. PCT: procalcitonin; BSI: blood stream infection.