Initial Treatment group | Consolidation Treatment | Follow-up period | Study Identification/Year of Enrolment (Ref) | Total patients |
---|---|---|---|---|
Artemether ir*, single dose | Artemether ir | 7 days | Aceng 2002–3 [32] | 51 |
Artemisinin ir, single dose | Mefloquine + SP | 72 hours | Hien 1998 | 46 |
Artemisinin ir, multiple dose | Mefloquine | None post discharge | Phuong 1992–5 [31] | 46 |
 |  |  | Vinh 1992–4 [33] | 52 |
Artesunate ir, multiple dose | Artesunate + SP | 72 hours | Karunajeewa 2003–4 [34] | 41 |
 | Mefloquine | 28 days | Looareesuwan 1995 [35] | 60 |
 |  |  | Than 1998 | 100 |
 |  | None post discharge | Bhatt 1994–5 [36] | 23 |
 | Chloroquine or SP | None post discharge | Karunajeewa 2001 [37] | 48 |
Artesunate ir, single dose | Artesunate + Mefloquine | 28–42 days | Van Vugt 1997–9 | 44 |
 |  | 28 days | Looareesuwan 2000 | 69 |
 | Mefloquine | 28 days | Looareesuwan 1996 | 26 |
 | Chloroquine or SP | 30 days | Krishna 1996 [10] | 23 |
 | SP | 28–42 days | Molyneux 1997–8 [30] | 113 |
 | Mefloquine-SP | 72 hours | Hien 1998 | 44 |
Artesunate per os | Artesunate + Mefloquine | 28–42 days | Van Vugt 1997–9 | 17 |
Artemisinins parenteral | Artesunate + SP | 72 hours | Karunajeewa 2003–4 [34] | 38 |
 | Mefloquine | 28 days | Looareesuwan 1996 | 24 |
 |  | None post discharge | Phuong 1992–5 [31] | 40 |
 |  |  | Vinh 1992–4 [33] | 123 |
 | Chloroquine or SP | 30 days | Krishna 1996 [10] | 11 |
Quinine parenteral | Quinine | 7 days | Aceng 2002–3 [32] | 52 |
 | SP | 28–42 days | Barnes 1998 [30] | 36 |
 |  | None post discharge | Phuong 1992–5 [31] | 35 |
Quinine parenteral + Artesunate ir | SP | 42 days | Barnes 1998 [30] | 5 |
Grand Total | Â | Â | Â | 1167 |