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Table 8 Positive SeptiFast® and negative blood culture: Isolated Pathogens per Patient with positive SF and negative blood culture result

From: Clinical impact of a commercially available multiplex PCR system for rapid detection of pathogens in patients with presumed sepsis

Pathogen

Therapeutical relevance

Coagulase negative Staphylococci

No change, empirical therapy sufficient and probable contamination

Enterococcus faecium

No change, empirical therapy sufficient

Enterococcus faecium

Modification necessary: Vancomycin added

Enterococcus faecium

No change, empirical therapy sufficient

Enterococcus faecium, Klebsiella pneumoniae, Enterobacter cloacae/aerogenes

No change, empirical therapy sufficient

Escherichia coli

No change: patient deceased before results became available, empirical therapy sufficient

Candida krusei

No change, empirical therapy sufficient

Streptococcus species

No change, empirical therapy sufficient

Enterococcus faecium

Modification necessary: Vancomycin added

Staphylococcus aureus

No change, empirical therapy sufficient

Enterococcus faecium, Candida glabrata

Modification necessary: Voriconazole added

Aspergillus fumigatus

Modification necessary: Voriconazole added. Growth of colonies from broncho-alveolar-lavage Aspergillus-Ag elevated.

Candida albicans

Modification necessary: Caspofungin added