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Table 2 Comparison of resistance patterns between Shigella flexneri and Shigella sonnei isolated in southern Vietnam between 1995 and 2008.

From: A changing picture of shigellosis in southern Vietnam: shifting species dominance, antimicrobial susceptibility and clinical presentation

Collection

Serotype (n)

Phenotypeb

AMP

CHL

SXT

TET

NAL

OFX

CRO

A (1995 - 1996)

sonnei (24)

R

11

8

23

23

0

0

0

  

S

13

16

1

1

24

24

24

 

flexneri (56)

R

54

10

53

53

9

0

0

  

S

2

46

3

3

47

56

56

p Valuea

  

< 0.0001

0.1287

0.8102

0.8102

0.0371

-

-

B (2000 - 2002)

sonnei (54)

R

50

10

53

52

9

0

1

  

S

4

44

1

2

45

54

53

 

flexneri (50)

R

46

38

44

49

21

0

0

  

S

4

12

6

1

29

50

50

p Valuea

  

0.9316

< 0.0001

0.0415

0.5577

0.0052

-

0.329

C (2007 - 2008)

sonnei (71)

R

17

5

71

69

51

0

12

  

S

54

66

0

2

20

71

59

 

flexneri (30)

R

25

28

28

30

19

1

1

  

S

5

2

2

0

11

29

29

p Valuea

  

< 0.0001

< 0.0001

< 0.0001

0.3696

0.4619

0.297

0.076

Combined

sonnei (148)

R

78

23

147

144

60

0

13

  

S

70

125

1

4

88

148

135

 

flexneri (136)

R

125

76

125

132

49

1

1

  

S

11

60

11

4

87

135

135

p Valuea

  

< 0.0001

< 0.0001

0.001

0.613

0.365

0.478

0.002

  1. a p Value calculated using the chi-squared test
  2. b Phenotype with respect to Resistant (R) or Sensitive (S)
  3. AMP; Ampicillin, CHL; Chloramphenicol, SXT; Trimethoprim- Sulfamethoxazole, TET; Tetracycline, NAL; Nalidixic Acid, OFX; Ofloxacin, CRO; Ceftriaxone.