From: Early severe morbidity and resource utilization in South African adults on antiretroviral therapy
Disease category | HAART (n = 70) n (%) | No-HAART (n = 60) n (%) | p-value |
---|---|---|---|
AIDS | 27* (39%) | 38 (63%) | p = 0.005 |
Tuberculosis | 17 | 28 | |
Cryptococcal meningitis | 5 | 3 | |
Cryptosporidiosis | 2 | 0 | |
Pneumocystis pneumonia | 1 | 6 | |
Kaposi sarcoma | 1 | 0 | |
HIV encephalopathy | 1 | 0 | |
Esophageal candidiasis | 0 | 1 | |
Drug reactions | 24 (34%) | 4 (7%) | p < 0.001 |
Hepatitis | 7 | 3 | |
Stevens-Johnson syndrome | 0 | 1 | |
Anemia (zidovudine) | 6 | ||
Lactic acidosis (stavudine) | 5 | ||
Neuropathy (stavudine) | 2 | ||
Pancreatitis (stavudine or lamivudine) | 1 | ||
Emesis (nevirapine) | 1 | ||
Rechallenge HAART | 1 | ||
Myopathy (zidovudine) | 1 | ||
HIV-related conditions | 7 (10%) | 6 (10%) | p = 1 |
Severe bacterial infection | 6 | 4 | |
Chronic diarrhea | 1 | 0 | |
HIV cardiomyopathy | 0 | 2 | |
Other conditions | 12 (17%) | 12 (20%) | p = 0.676 |
Aseptic meningitis | 5 | 2 | |
TB sequelae | 3 | 0 | |
Deep venous thrombosis | 2 | 4 | |
Drug overdose | 1 | 0 | |
Hematologic disorder | 1 | 1 | |
Renal failure | 0 | 1 | |
Stroke | 0 | 1 | |
Diabetic complications | 0 | 1 | |
Reactive arthritis | 0 | 1 | |
Palliative care | 0 | 1 |