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Table 1 Clinical characteristics of patients with pneumococcal pneumonia according to penicillin susceptibility.

From: Drug-resistance in Streptococcus pneumoniae isolates among Spanish middle aged and older adults with community-acquired pneumonia

 

Penicillin-Susceptible strains

N = 77

Penicillin-Resistant strains

N = 27

P-value*

Overall Strains

N = 104

Age (yrs), mean (SD)

70.3 (11.8)

76.4 (9.5)

0.018

71.9 (11.6)

Sex:

    

   Male

56 (72.7)

19 (70.4)

0.814

75 (72.1)

   Female

21 (27.3)

8 (29.6)

 

29 (27.9)

Underlying conditions

    

   Chronic pulmonary disease

26 (33.8)

9 (33.3)

0.967

35 (33.7)

   Chronic hearth disease

18 (23.4)

8 (29.6)

0.519

26 (25)

   Diabetes Mellitus

15 (19.5)

7 (25.9)

0.480

22 (21.2)

   Stroke

5 (6.5)

2 (7.4)

0.870

7 (6.7)

   Chronic liver disease

7 (9.1)

2 (7.4)

0.949

9 (8.7)

   Chronic renal disease

10 (13.0)

7 (25.9)

0.118

17 (16.3)

   Cancer

8 (10.4)

4 (14.8)

0.536

12 (11.5)

   Alcoholism

11 (14.3)

0 (0)

0.038

11 (10.6)

   Smoker

25 (32.5)

5 (18.5)

0.169

30 (28.8)

   Corticosteroid therapy

3 (3.9)

3 (11.1)

0.166

6 (5.8)

Risk strata of patients

    

   High

21 (27.2)

10 (37)

0.477

31 (29.8)

   Moderate

36 (46.8)

10 (37)

0.516

46 (44.2)

   Low

20 (26)

7 (25.9)

0.802

27 (26.0)

PSI classes

    

   PSI I-III

18 (23.4)

7 (25.9)

0.790

25 (24.1)

   PSI IV-V

59 (76.6)

20 (74.1)

 

79 (75.9)

  1. NOTE: Data are numbers (percentage) of subjects, unless otherwise indicated. SD, standard deviation. PSI, pneumonia severity index.
  2. * P-values were calculated by using Student's t test for continuous variables and chi-squared or Fisher's test for categorical variables, as appropriate.