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Table 4 Diagnostic accuracy of serum PCT for the diagnosis of nosocomial infection.

From: Serum procalcitonin for the early recognition of nosocomial infection in the critically ill patients: a preliminary report

PCT value

AUROCC

(95% CI)

cut-off value

Sensitivity

(%)

Specificity

(%)

Positive

predictive

value (%)

Negative

predictive

value (%)

LR+

LR-

PCT D0

0.80

(0.68–091)

0.44

65.2

83.0

83.0

65.2

3.83

0.42

ΔPCTD-1, D0 *

0.89

(0.79–0.98)

+0.26

75.8

100

100

68.0

NA

0.24

ΔPCTD-2, D0 **

0.89

(0.75–0.96)

+0.20

67.9

100

100

64.0

NA

0.32

ΔPCTD-3, D0 ***

0.84

(0.71–0.93)

+0.21

61.8

100

100

56.7

NA

0.38

  1. PCT: procalcitonin; AUROCC: Area Under the Receiver Operating Characteristic Curve; CI: Confidence Interval; LR: Likelihood Ratio; NA: not applicable
  2. ΔPCTD-1, D0 = PCT D0 – PCT D-1; D0: day when infection is clinically suspected.
  3. *available in 45 out of the 70 included patients; **available in 44 out of the 70 included patients; ***available in 51 out of the 70 included patients.