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Table 4 Genotype and allele frequencies of tagSNPs in MASP2 in SARS patients and controls from Beijing, and their association with risk of SARS

From: Lack of association between polymorphisms of MASP2and susceptibility to SARS coronavirus infection

 

SARS cases

(n = 272)

Controls

(n = 232)

P value

rs2261695

   

Genotype

   

AA

189 (70.3%)

174 (75.0%)

0.49

AG

77 (28.6%)

56 (24.1%)

 

GG

3 (1.1%)

2 (0.9%)

 

Allele

   

A

455 (84.6%)

404 (87.1%)

0.26

G

83 (15.4%)

60 (12.9%)

 

rs2273346

   

Genotype

   

TT

186 (68.4%)

147 (63.4%)

0.19

TC

78 (28.7%)

71 (30.6%)

 

CC

8 (2.9%)

14 (6.0%)

 

Allele

   

T

450 (82.7%)

365 (78.7%)

0.10

C

94 (17.3%)

99 (21.3%)

 

rs12711521

   

Genotype

   

TT

105(38.5%)

106(45.7%)

0.11

TG

137(50.5%)

95(40.9%)

 

GG

30(11.0%)

31(13.4%)

 

Allele

   

T

347 (63.8%)

307(66.2%)

0.43

G

197 (36.2%)

157(33.8%)

 

rs7548659

   

Genotype

   

TT

173 (69.5%)

157 (67.7%)

0.27

TG

61 (24.5%)

67 (28.9%)

 

GG

15 (6.0%)

8 (3.4%)

 

Allele

   

T

407 (81.7%)

381(82.1%)

0.87

G

91 (18.3%)

83(17.9%)

 

Diplotypea

   

TT

344(63.2%)

304(65.5%)

0.29

TG

108(19.9%)

60(12.9%)

 

CT

6(1.1%)

2(0.5%)

 

CG

86(15.8%)

98(21.1%)

 
  1. aTwo SNP diplotypes span the genomic region of exon 9 (rs2273346 and rs12711521).