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Table 6 The joined analysis of the Beijing and Guangzhou population

From: Lack of association between polymorphisms of MASP2and susceptibility to SARS coronavirus infection

 

SARS cases

controls

   

Genotype

P1

P2

C1

C2

P1 vs.P2

C1vs.C2

P1, P2 vs. C1, C2

 

(n = 272)

(n = 104)

(n = 232)

(n = 291)

P

P

P

rs2261695

       

AA

189 (70.3%)

73

(75.3%)

174 (75.0%)

193

(70.4%)

0.35

0.25

0.76

AG

77

(28.6%)

22

(22.7%)

56

(24.1%)

78

(28.5%)

   

GG

3

(1.1%)

2

(2.0%)

2

(0.9%)

3

(1.1%)

   

rs2273346

       

TT

186 (68.4%)

64

(61.5%)

147

(63.4%)

190

(66.2%)

0.21

0.50

0.63

TC

78 (28.7%)

36

(34.6%)

71

(30.6%)

82

(28.6%)

   

CC

8

(2.9%)

4

(3.8%)

14

(6%)

15

(5.2%)

   

rs12711521

       

TT

105

(38.5%)

58

(55.8%)

106

(45.7%)

139

(47.8%)

0.003

0.64

0.30

TG

137

(50.5%)

36

(34.6%)

95

(40.9%)

108

(37.1%)

   

GG

30

(11.0%)

10

(9.6%)

31

(13.4%)

44

(15.1%)

   

rs7548659

       

TT

173

(69.5%)

70

(67.3%)

157

(67.7%)

205

(70.5%)

0.69

0.50

0.91

TG

61 (24.5%)

25

(24.0%)

67

(28.9%)

75

(27.8%)

   

GG

15

(6.0%)

9

(8.7%)

8

(3.4%)

11

(1.7%)

   

Diplotypea

       

TT

344

(63.2%)

128

(61.5%)

304

(65.5%)

380

(65.3%)

0.89

1.00

0.31

TG

108

(19.9%)

42

(20.2%)

60

(12.9%)

76

(13.0%)

   

CT

6

(1.1%)

4

(1.9%)

2

(0.5%)

4

(0.7%)

   

CG

86

(15.8%)

34

(16.4%)

98

(21.1%)

122

(21.0%)

   
  1. P1:SARS patients from Beijing; P2: SARS patients from Guangzhou; C1:controls from Beijing; C2:controls from Guangzhou.