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Table 5 Percentage of HPV positive infants at different points during follow-up according to mother's HPV status and specific genotypes detected in mother/child HPV positive pairs.

From: Human Papillomavirus (HPV) infection in pregnant women and mother-to-child transmission of genital HPV genotypes: a prospective study in Spain

 

Infants' HPV positivity by follow-up period

Mothers' HPV status

at 0 to 6 days

at 6 weeks

at 3 to 24

months

Any time

(0 to 24 months)

 

% (HPV+/tested)

% (HPV+/tested)

% (HPV+/tested)

% (HPV+/tested)

At pregnancy

    

HPV negative

3.1% (2/64)

11.9% (7/59)

7.4% (4/54)

16.9% (13/77)

HPV positive

9.4% (5/53)

13.7% (7/51)

11.8% (4/34)

19.7% (13/66)

Mother/child HPV positive pairs with concordant genotypes

[types in mother/child pairs]

1 of 5

[16,6,11/6,11]

2 of 7

[16/16; 18/18]

2 of 4

[16/16; 18/18]

4 of 13

[16,6,11/6,11; 16/16; 16/16; 18/18]

Mother/child HPV positive pairs with discordant genotypes

[types in mother/child pairs]

4 of 5

[18/6,11; X/X; X/X; X/31]

5 of 7

[18/6,11; 18/6,11; X/X; X/X; 16/X]

2 of 4

[6,11/16; X/X]

9 of 13

[18/6,11; 18/6,11; 6,11/16; X/31; X/X; X/X; X/X; X/X; X/X]

Fisher's exact test*

0.2

0.8

0.7

0.7

At 6 weeks postpartum

    

HPV negative

2.7% (2/74)

7.2% (6/83)

6.2% (4/65)

12.9% (12/93)

HPV positive

11.1% (2/18)

27.3% (6/22)

21.4% (3/14)

32.0% (8/25)

Mother/child HPV positive pairs with concordant genotypes

[types in mother/child pairs]

0 of 2

2 of 6

[18,6,11/6,11; 18/18]

2 of 3

[18/18; 16,6,11/16]

3 of 8

[18,6,11/6,11; 18/18; 16,6,11/16]

Mother/child HPV positive pairs with discordant genotypes

[types in mother/child pairs]

2 of 2

[16/X; 18/6,11]

4 of 6

[18/6,11; X/X; 16,6,11/X; X/6,11]

1 of 3

[6,11/16]

5 of 8

[18/6,11; 6,11/16; X/X; 16/X; X/6,11]

Fisher's exact test*

0.2

0.02

0.1

0.03

  1. * For the association between HPV status in mother and HPV status in child