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Table 3 Clinical characteristics of confirmed cases at the time of hospital admission

From: Clinical characteristics of the autumn-winter type scrub typhus cases in south of Shandong province, northern China

Clinical symptoms   Present study
N = 480 (%)
Other study [28]
N = 274 (%)
P-value
Typical symptoms of scrub typhus     
  Fever 480(100.0) 274(100.0) --
  Maculopapular rashes appeared on the trunk and proximal limbs 434 (90.4) 102(37.2) < 0.001a
  Skin eschars 425 (88.5) 240(87.6) 0.697 a
  Regional lymphadenopathy 291 (60.6) 248(90.5) < 0.001a
General symptoms of febrile disease     
  Chills 323 (67.3) 125(45.6) < 0.001a
  Loss of appetite 398 (82.9) 243(88.7) 0.033a
  Erythematous flushes on the face, neck and upper bosom 234 (48.8) -- --
  Myalgia and prostration 480 (100.0) 250(91.2) < 0.001a
Ache     
  Headache 480 (100.0) 135(49.3) < 0.001b
  Retro-orbital pain 83 (17.3) 188(68.6) < 0.001a
Heart damage     
  Electrocardiogram abnormity 38 (7.9) 74(27.0) < 0.001a
  Toxic myocarditis 0 57(20.8) < 0.001b
Digestive system damage     
  Abdominal pain 234 (48.8) 67(24.5) < 0.001b
  Nausea/vomiting 210 (43.8) 62(22.6) < 0.001a
  Hepatosplenomegaly 84 (17.5) 166(60.6) < 0.001b
  Alimentary tract hemorrhage 0 34(12.4) < 0.001b
  Pleural fluid, or abdominal dropsy 0 27(9.9) < 0.001b
Kidney damage     
  Flank tenderness 48 (10.0) 86(31.39) < 0.001 a
  1. a – Chi-square test; b – Fisher's exact test.