Deaths among tuberculosis cases in Shanghai, China: who is at risk?

BMC Infectious Diseases

Table 2 Results of the univariate and multivariate analysis of the characteristics of tuberculosis (TB) patients associated with death during anti-TB treatment, Shanghai, 2000–2004

Characteristics	Survived		Died		OR	(95% CI)	P value	AOR	(95% CI)	P value
	No.	(%)	No.	(%)
Age (years)
11–29	1034	(13.9)	2	(0.5)	1.0			1.0
30–44	1624	(21.8)	19	(4.3)	6.0	(1.5–53.6)	0.006	5.0	(1.2–21.7)	0.031
45–59	1924	(25.9)	42	(9.5)	11.3	(2.9–96.4)	<0.001	8.2	(2.0–34.3)	0.004
60–74	1883	(25.3)	174	(39.5)	47.8	(13.0–398.1)	<0.001	35.4	(8.7–143.6)	<0.001
≥ 75	968	(13.0)	203	(46.1)	108.4	(29.5–902.7)	<0.001	82.3	(20.3–333.2)	<0.001
Sex
Female	1681	22.6	55	12.5	1.0			1.0
Male	5752	77.4	385	87.5	2.0	(1.5–2.8)	<0.001	1.7	(1.2–2.3)	0.001
Case type
New case	6056	81.5	327	74.3	1.0			-
Retreatment case	1377	18.5	113	25.7	1.5	(1.2–1.9)	<0.001	-
Cavity on initial chest radiograph
Absent	4943	66.5	315	71.6	1.0			-
Present	2266	30.5	110	25.0	0.8	(0.6–0.9)	0.016	-
Uncertain	224	3.0	15	3.4	-			-
Sputum Smear
Negative	1461	18.6	1416	19.0	1.0			1.0
Positive	6334	80.4	5945	80.0	2.1	(1.5–2.9)	<0.001	1.6	(1.2–2.2)	0.004
Unknown	78	1.0	72	1.0	-			-
Comorbidity
Absent	5938	79.9	293	66.6	1.0			1.0
Present	1466	19.7	142	32.3	2.0	(1.6–2.4)	<0.001	1.4	(1.1–1.7)	0.004
Unknown	29	0.4	5	1.1	-			-
Drug susceptibility results
Non-MDR	4487	60.4	227	51.6	1.0			-
MDR	241	3.2	15	3.4	1.2	(0.7–2.1)	0.450	-
Unknown	2705	36.4	198	45.0	1.4	(1.2–1.8)	<0.001	-

TB = tuberculosis; OR = odds ratio; AOR = adjusted odds ratio; CI = confidence interval; MDR = multidrug resistance

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