Covariate | Category | HPVI | 6MPI | ||||||
---|---|---|---|---|---|---|---|---|---|
No. of women (N = 982) | No. of women with HPVI (N = 496) | HR (95% CI) | p-value | No. of women (N = 982) | No. of women with 6MPI (N = 281) | HR (95% CI) | p-value | ||
Region | Europe | 644 | 345 | 1 | 644 | 201 | 1 | ||
Asia Pacific | 168 | 58 | 1.11 (0.81-1.52) | 0.5055 | 168 | 36 | 1.21 (0.78-1.86) | 0.3995 | |
Latin America | 76 | 46 | 1.16 (0.84-1.60) | 0.3627 | 76 | 24 | 0.99 (0.63-1.57) | 0.9773 | |
North America | 94 | 47 | 0.88 (0.64-1.20) | 0.4273 | 94 | 20 | 0.75 (0.47-1.20) | 0.2283 | |
0.5498 | 0.4934 | ||||||||
Number of lifetime sexual partners1 | 1 | 800 | 234 | 1 | 800 | 127 | 1 | ||
2-3 | 430 | 190 | 4.76 (3.82-5.95) | <0.0001 | 470 | 111 | 4.19 (3.12-5.63) | <0.0001 | |
≥4 | 125 | 72 | 19.22 (14.02-26.34) | <0.0001 | 166 | 43 | 14.14 (9.35-21.37) | <0.0001 | |
<0.0001 | <0.0001 | ||||||||
History of Chlamydia trachomatis during the past 12 months1 | No | 977 | 463 | 1 | 978 | 257 | 1 | ||
Yes | 60 | 33 | 3.00 (2.07-4.36) | <0.0001 | 73 | 24 | 2.50 (1.57-4.00) | 0.0001 | |
<0.0001 | 0.0001 | ||||||||
Cumulative duration of hormone use for contraception or other indication1 | No use | 804 | 105 | 1 | 804 | 59 | 1 | ||
1-12 months | 727 | 173 | 2.18 (1.68-2.83) | <0.0001 | 746 | 111 | 2.10 (1.48-2.98) | <0.0001 | |
13-48 months | 536 | 206 | 3.26 (2.45-4.34) | <0.0001 | 590 | 108 | 2.79 (1.91-4.09) | <0.0001 | |
>48 months | 56 | 11 | 5.42 (2.84-10.36) | <0.0001 | 69 | 2 | 1.62 (0.39-6.74) | 0.5107 | |
<0.0001 | <0.0001 | ||||||||
Marital/partner status1 | Living or lived with partner | 238 | 42 | 1 | 271 | 19 | 1 | ||
Single | 961 | 454 | 1.45 (1.04-2.04) | 0.0291 | 963 | 262 | 1.75 (1.01-3.03) | 0.0445 | |
0.0291 | 0.0445 | ||||||||
Tobacco exposure (number of pack-years)1 | <0.5 | 862 | 402 | 1 | 862 | 223 | 1 | ||
≥0.5 | 153 | 94 | 1.17 (0.92-1.47) | 0.1936 | 161 | 58 | 1.22 (0.90-1.66) | 0.2085 | |
0.1936 | 0.2085 | ||||||||
Previous cervical HPV infection1 | No | - | - | - | - | 965 | 231 | 1 | |
Yes | - | - | - | - | 188 | 38 | 0.49 (0.33-0.72) | 0.0003 | |
- | 0.0003 |