Table 2 Reasons for regimen modification (n = 377)
Reasons | Number (%) | Days to regimen modification |
|---|---|---|
(Median, IQRa) | ||
Adverse effects | 277 (73.5) | 29 (5-55) |
 Lipodystrophy | 175 (63.2) | 1493 (936-1946) |
 Rash | 49 (17.7) | 29 (24-44) |
 Hepatitis/Liver dysfunction | 33 (11.9) | 146 (56-315) |
 Lactic acidosis | 9 (3.3) | 511 (410-573) |
 Neuropathy | 8 (2.9) | 506 (286-574) |
 Others | 3 (1.1) | 545 (388-1769) |
Treatment failure | 63 (16.7) | 1147 (344-1246) |
For TBb treatment | 16 (4.2) | 186 (93-248) |
Pregnancy | 10 (2.7) | 868 (682-1643) |
Others | 2 (0.5) | 527 (62-992) |
Unknown | 9 (2.4) | 1085 (527-1705) |