Table 4 Predictors of regimen modification due to rash

Gender

  Male

1

1

  Female

1.83 (1.03-3.27)

0.04

1.82 (0.99-3.34)

0.05

Age

  <35

1

1

  ≥35

1.20 (0.69-2.10)

0.51

1.08 (0.60-1.93)

0.81

Clinical status

  Asymptomatic

1

1

  Symptomatic

0.45 (0.19-1.09)

0.08

0.52 (0.21-1.28)

0.15

  AIDS

0.61 (0.31-1.22)

0.16

0.94 (0.44-2.03)

0.88

CD4 cell count

  >200

1

0.75

1

0.60

  50-199

1.21 (0.37-3.98)

1.38 (0.41-4.63)

  <50

0.70 (0.21-2.39)

0.58

0.71 (0.20-2.55)

0.60

HLA-B*35:05

  No

1

1

  Yes

8.24 (3.51-19.4)

<0.001

7.73 (3.16-18.9)

<0.001

HLA-B*57:01

No

1

1

Yes

1.70 (0.23-12.3)

0.60

2.06 (0.28-15.4)

0.48