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Table 2 Associations between lifestyle factors and serological reactivity for HPV16

From: Determinants of baseline seroreactivity to human papillomavirus type 16 in the Ludwig-McGill cohort study

Characteristic and categories

HPV16 seroreactivity 425/1624 (%)*

OR (95%CI)**

Unadjusted

Adjusted (HPV16 and age)

Smoking:

   

Never

216/768 (22.0)

1.0

1.0

Current

124/581 (17.6)

0.75 (0.59-0.97)

0.74 (0.58-0.98)

Former

85/275 (23.6)

1.09 (0.82-1.46)

1.06 (0.79-1.42)

Smoking duration:

   

Never

216/768 (22.0)

1.0

1.0

<=10 years

86/379 (18.5)

0.81 (0.61-1.07)

0.81 (0.61-1.07)

11+ years

95/413 (18.7)

0.82 (0.62-1.07)

0.62 (0.57-0.98)

Drinking:

   

Never

131/556 (19.1)

1.0

1.0

Ever drinker

291/1064 (21.5)

1.16 (0.92-1.47)

1.16 (0.92-1.47)

Lifetime sexual partners:

   

0-1

132/770 (14.6)

1.0

1.0

2-3

162/555 (22.6)

1.70 (1.32-2.19)

1.70 (1.32-2.20)

4-5

84/181 (31.7)

2.71 (1.97-3.72)

2.56 (1.97-3.53)

6+

47/117 (28.7)

2.34 (1.59-3.44)

2.29 (1.55-3.37)

Sexual partners, last 5 years:

  

0-1

321/1262 (20.3)

1.0

1.0

2-3

83/290 (22.2)

1.12 (0.86-1.48)

1.17 (0.88-1.55)

4+

20/71 (22.0)

1.10 (0.66-1.84)

1.30 (0.77-2.19)

Sexual partners, last year:

   

0-1

400/1534 (20.7)

1.0

1.0

2-3

15/69 (17.9)

0.83 (0.47-1.47)

0.90 (0.51-1.60)

4+

2/5 (28.6)

1.53 (0.29-7.93)

1.89 (0.36-9.87)

Age at first sexual intercourse:

  

20-50

89/446 (16.6)

1.0

1.0

18-19

89/344 (20.6)

1.30 (0.93-1.79)

1.52 (1.08-2.13)

16-17

107/417 (20.4)

1.29 (0.94-1.76)

1.60 (1.15-2.23)

<=15

140/417 (25.1)

1.68 (1.25-2.27)

2.18 (1.59-3.00)

Frequency of sex (weekly):

   

0-1 times

224/865 (20.6)

1.0

1.0

2-3

133/576 (18.8)

0.89 (0.70-1.13)

0.95 (0.75-1.22)

4-5

42/123 (25.5)

1.31 (0.90-1.92)

1.53 (1.04-2.26)

6+

25/58 (30.1)

1.66 (1.01-2.72)

1.77 (1.07-2.92)

Practice of anal sex:

   

Never

254/1018 (20.0)

1.0

1.0

Ever

171/606 (22.0)

1.13 (0.91-1.41)

1.14 (0.92-1.42)

Practice of oral sex:

   

Never

195/739 (20.9)

1.0

1.0

Ever

230/885 (20.6)

0.98 (0.79-1.22)

1.08 (0.87-1.34)

  1. *Frequencies above and below the threshold for the top 20% quintile and percentage with high seroreactivity; **Odds ratios and respective 95% confidence intervals. First category in each variable is the referent.