Table 3 The association between two SNPs within the FTO gene and the risk of tuberculosis

TT

1250(80.91)

1258(79.52)

1

1

856(79.48)

1

1

AT

275(17.86)

253(15.94)

0.91(0.75-1.10)

0.316

0.91(0.74-1.10)

0.316

182(16.90)

0.96(0.78-1.18)

0.723

0.96(0.77-1.19)

0.699

AA

19(1.23)

72(4.54)

3.77(2.26-6.28)

<0.001

3.57(2.13-6.01)

<0.001

39(3.62)

2.99(1.73-5.17)

<0.001

2.84(1.61-5.01)

<0.001

T allele

2767(89.84)

2777(87.35)

1

1894(87.93)

1

A allele

313(10.16)

397(12.51)

1.26(1.08-1.48)

0.004

260(12.07)

1.21(1.02-1.44)

0.030

Add

1.23(1.06-1.42)

0.006

1.22(1.05-1.42)

0.011

1.20(1.01-1.41)

0.035

1.18(0.99-1.40)

0.059

Dom

1.10(0.92-1.31)

0.296

1.09(0.91-1.30)

0.374

1.10(0.90-1.34)

0.343

1.09(0.89-1.33)

0.424

Rec

3.82 (2.30-6.37)

<0.001

3.64(2.17-6.10)

<0.001

3.02(1.73-5.25)

<0.001

2.86(1.62-5.04)

<0.001

CC

1250(80.91)

1265(79.96)

1

1

863(80.13)

1

1

AC

282(18.31)

311(19.60)

1.09(0.91-1.30)

0.347

1.08(0.19-1.26)

0.408

210(19.5)

1.08(0.89-1.32)

0.448

1.07(0.87-1.32)

0.513

AA

12(0.78)

7(0.44)

0.58(0.23-1.47)

0.248

0.48(0.19-1.26)

0.136

4(0.37)

0.48(0.16-1.50)

0.209

0.40(0.13-1.28)

0.123

C allele

2774(90.06)

2849(89.76)

1

1936(89.88)

1

A allele

306(9.94)

325(10.24)

1.03 (0.88-1.22)

0.690

218(10.12)

1.02(0.85-1.23)

0.826

Add

1.04(0.88-1.23)

0.632

1.02(0.86-1.22)

0.804

1.03(0.85-1.24)

0.789

1.01(0.83-1.22)

0.957

Dom

1.07(0.90-1.28)

0.461

1.05(0.88-1.27)

0.569

1.06(0.87-1.28)

0.590

1.04(0.85-1.28)

0.702

Rec

0.57 (0.22-1.44)

0.234

0.48(0.18-1.24)

0.127

0.48(0.15-1.48)

0.200

0.40(0.12-1.26)

0.117*