| All population | "when-to-start" guidelines | "what-to-start" guidelines | ||||
---|---|---|---|---|---|---|---|
Characteristic | N = 1,365 | Followed guidelines (n = 1,214) | Outside of guidelines (n = 151) | P | Followed guidelines (n = 1,215) | Outside of guidelines (n = 150) | P |
cART modification (%) | 43.6 | 43.7 | 43.4 | - | 41.2 | 62.7 | <0.001 |
12 months CD4 (/mm3) (median [IQR]) | 395 | 369 | 619 | <0.001 | 406 | 313 | <0.001 |
[241-538] | [224-506] | [504-766] | [257-548] | [148-484] | |||
CD4 gain (/mm3) (median [IQR]) | 137 | 139 | 89 | 0.006 | 144 | 69 | <0.001 |
[33-238] | [39-239] | [0-216] | [40-239] | [0-204] | |||
12 months HIV-RNA (log copies/mL) (median [IQR]) | 1.7 | 1.7 | 1.7 | - | 1.7 | 1.9 | <0.001 |
[1.6-2.3] | [1.6-2.3] | [1.7-2.4] | [1.6-2.2] | [1.7-3.4] | |||
HIV-RNA <50 copies/mL (%) | 64.6 | 64.3 | 66.9 | - | 66.8 | 47.3 | <0.001 |
Deceased (%) | 0.8 | 0.9 | 0 | - | 0.6 | 2.7 | 0.007 |