Table 3 Effectiveness and cost of tetanus immunity diagnostic strategies in wounded patients in French ED a,b
Cohort | Strategies | Tetanus case | Effectiveness (LY) | Vaccine dose | TIG dose | TQS cost | Prophylaxis cost | Total cost |
|---|---|---|---|---|---|---|---|---|
All wounded patients | Medical Interview | 0.41 | 58,658,086.40 | 1,033,000 | 320,000 | - | € 21,478,000 | € 21,564,000 |
N =1,658,000 | TQS | 0.02 | 58,658,087.40 | 601,000 | 186,000 | € 6,866,000 | € 12,490,000 | € 19,361,000 |
ΔC | -0.39 | 1 | -432,000 | -134,000 | € 6,866,000 | -€ 8,988,000 | -€ 2,203,000 | |
Patients with a | Medical Interview | 0.13 | 40,494,923.00 | 713,000 | - | - | € 7,118,000 | € 7,145,000 |
Non-tetanus-prone wound | TQS | 0.01 | 40,494,923.30 | 415,000 | - | € 4,740,000 | € 4,139,000 | € 8,881,000 |
N =1,145,000 | Δ | -0.13 | 0.3 | -298,000 | - | € 4,740,000 | -€ 2,979,000 | € 1,736,000 |
Patients with a | Medical Interview | 0.28 | 18,163,163.40 | 320,000 | 320,000 | - | € 14,360,000 | € 14,419,000 |
Tetanus-prone-wound | TQS | 0.02 | 18,163,164.10 | 186,000 | 186,000 | € 2,126,000 | € 8,351,000 | € 10,480,000 |
N =513,000 | Δ | -0.26 | 0.7 | -134,000 | -134,000 | € 2,126,000 | -€ 6,009,000 | -€ 3 939,000 |
Patients 18-64 years | Medical Interview | 0.04 | 56,180,160.90 | 838,000 | 260,000 | € 17,048,000 | € 17,438,000 | |
N =1,383,000 | TQS | 0 | 56,180,161.00 | 469,000 | 145,000 | € 5,726,000 | € 9,755,000 | € 15,482,000 |
Δ | -0.04 | 0.10 | -369,000 | -115,000 | € 5,726,000 | -€ 7,293,000 | -€ 1,956,000 | |
Patients of 65 | Medical Interview | 0.37 | 2,477,925.50 | 195,000 | 60,000 | - | € 4,430,000 | € 4,126,000 |
Years and over | TQS | 0.02 | 2,477,926.40 | 132,000 | 41,000 | € 1,140,000 | € 2,735,000 | € 3,879,000 |
N =275,000 | Δ | -0.35 | 0.9 | -63,000 | -19,000 | € 1,140,000 | -€ 1,695,000 | -€ 247,000 |