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Table 5 Serological follow-up of cases and controls

From: Persistent high antibody titres against Coxiella burnetiiafter acute Q fever not explained by continued exposure to the source of infection: a case-control study

Possible chronic Q fever

Possible chronic Q fever

Antibody titers on the 24 thmonth after acute Q fever diagnosis

IgG phase I

IgG phase II

Antibody titers on the 36 thmonth after acute Q fever diagnosis

IgG phase I

IgG phase II

<1:32

0 (0.0%)

0 (0.0%)

<1:32

0 (0.0%)

0 (0.0%)

1:32 - 1:128

2 (7.4%)

0 (0.0%)

1:32 - 1:128

1 (4.8%)

0 (0.0%)

1:256 - 1:512

7 (25.9%)

2 (7.4%)

1:256 - 1:512

7 (33.3%)

3 (14.3%)

1:1,024 - 1:2,048

12 (44.4%)

13 (48.1%)

1:1,024 - 1:2,048

10 (47.6%)

12 (57.1%)

≥1:4,096

6 (22.2%)

12 (44.4%)

≥1:4,096

3 (14.3%)

6 (28.6%)

IgG phase I

IgG phase II

Antibody titers on the 48 th month after acute Q fever diagnosis

Possible chronic Q fever

No chronic Q fever †

Antibody titers on the 48 th month after acute Q fever diagnosis

Possible chronic Q fever

No chronic Q fever †

<1:32

1 (2.9%)

55 (51.0%)

<1:32

0 (0.0%)

3 (2.8%)

1:32 - 1:128

6 (17.6%)

47 (43.9%)

1:32 - 1:128

0 (0.0%)

31 (29.0%)

1:256 - 1:512

11 (32.4%)

5 (4.7%)

1:256 - 1:512

5 (14.7%)

51 (47.7%)

1:1,024 - 1:2,048

10 (29.4%)

0 (0.0%)

1:1,024 - 1:2,048

19 (55.9%)

19 (17.8%)

≥1:4,096

6 (17.6%)

0 (0.0%)

≥1:4,096

10 (29.4%)

3 (2.8%)

p-value =0.001*

p-value =0.001*

  1. *Chi-square test is used to calculate the p-value.
  2. †There were three patients without chronic Q fever of which serological data of four years after acute Q fever diagnosis was missing.