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Table 6 Antimicrobial susceptibility profiles of microorganisms implicated in MC-CRBSI episodes

From: Surveillance of catheter-related infections: the supplementary role of the microbiology laboratory

Antimicrobial susceptibility profile according to antimicrobial category

% isolates resistant

S. epidermidis (n = 55)

S. aureus (n = 16)

A. baumannii complex (n = 35)

E. cloacae (n = 17)

P. aeruginosa (n = 14)

K. pneumoniae (n = 12)

Anti-staphylococcal β-lactams (oxacillin)

96

75

-

-

-

-

Penicillin (ampicillin)

-

-

-

-

-

100

β-lactamase inhibitors (amoxicillin/clavulanic acid)

-

-

100

-

-

33

β-lactamase inhibitors (piperacillin/tazobactam)

-

-

-

53

36

33

Cephamycins (cefoxitin)

-

-

-

-

-

17

Non-ES cephalosporins (cefuroxime)

-

-

-

71

-

33

ES cephalosporins (cefotaxime#, ceftazidime, cefepime)

-

-

100

53

21

33

Carbapenems (ertapenem#, meropenem, imipenem)

-

-

100

18

36

0

Aminoglycosides (amikacin*, gentamicin)

80

63

86

0

14

17

Fluoroquinolones (ciprofloxacin, moxifloxacin^)

55

75

49

0

14

17

Macrolides (erythromycin)

84

75

-

-

-

-

Linosamides (clindamycin)

76

63

-

-

-

-

Linezolid

0

0

-

-

-

-

Glycopeptides (teicoplanin, vancomycin)

0

0

-

-

-

-

Tetracycline

93

63

-

-

-

-

Glycylcycline (tigecycline)

0

0

3

12

-

17

Fusidic acid

24

0

-

-

-

-

Rifampicin

47

19

-

-

-

-

Polymyxins (colistin)

-

-

0

6

14

0

Folate pathway inhibitors (trimethoprim/ sulphamethoxazole)

78

75

-

12

-

17

Acquired resistance profiles

S

11

25

0

47

79

67

MDR

89

75

0

53

7

33

XDR

0

0

100

0

0

0

PDR

0

0

0

0

14

0

  1. ES = extended-spectrum; S = sensitive.
  2. MDR = multidrug-resistant, non-susceptible to ≥1 agent in ≥ 3 antimicrobial categories.
  3. XDR = extensively drug-resistant, non-susceptible to ≥ 1 agent in all but ≤ 2 antimicrobial categories.
  4. PDR = pandrug-resistant, non-susceptible to all antimicrobial agents tested [20].
  5. - = not applicable to the specific bacteria, #not tested (n/t) for in P. aeruginosa, *n/t for in Gram-positive bacteria,^n/t for in Gram-negative bacteria.