A nationwide population-based cohort study to identify the correlation between heart failure and the subsequent risk of herpes zoster

Table 4 Overall and age- and sex-specific incidence rate and relative hazard of Herpes Zoster in the heart failure and comparison cohorts

Variable	Case group			Control group			HR	AHR
Variable	Incident cases	Person-year	IR¹per 1000 patient-years	Incident cases	Person-year	IR¹per 1000 patient-years
Age^a
18-40	1	196.24	5.10 (−4.87-15.06)	1	590.34	1.69 (−1.62-5.01)	3.00 (0.19-47.92)	7.81 (0.28-215.54)
41-65	23	1341.56	17.14 (10.20-24.09)	22	4066.38	5.41 (3.16-7.66)	3.16 (1.76-5.68)***	3.14 (1.59-6.21)**
66-80	37	2092.79	17.68 (12.03-23.33)	72	6361.81	11.32 (8.72-13.92)	1.56 (1.05-2.32)*	1.66 (1.09-2.53)*
81-	22	1081.41	20.34 (11.93-28.76)	33	3278.74	10.06 (6.65-13.48)	2.02 (1.18-3.46)*	2.26 (1.29-3.96)**
Sex^b
Male	42	2514.55	16.70 (11.69-21.71)	61	7612.37	8.01 (6.01-10.02)	2.08 (1.41-3.08)***	2.30 (1.51-3.50)***
Female	41	2197.45	18.66 (13.00-24.32)	67	6684.89	10.02 (7.63-12.41)	1.86 (1.26-2.74)**	1.92 (1.27-2.92)**
Total	83	4712.00	17.61 (13.86-21.37)	128	14297.27	8.95 (7.41-10.50)	1.96 (1.49-2.59)***	2.07 (1.54-2.78)***

IR indicates incidence rate.
¹Based on the Poisson assumption.
^aAdjusted for patients’ Sex, Age, Urbanization level, Geographic region, Monthly income, Hypertension, Hyperlipidemia, Diabetes, COPD.
^bAdjusted for patients’ Age, Urbanization level, Geographic region, Monthly income, Hypertension, Hyperlipidemia, Diabetes, and COPD.
*Indicates p < 0.05; ** Indicates p < 0.01; *** Indicates p < 0.001.

ISSN: 1471-2334