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Table 1 Characteristics of study subjects segregated according to clinical status

From: Soluble MICB protein levels and platelet counts during hepatitis B virus infection and response to hepatocellular carcinoma treatment

Characteristics

ASYM (n = 48)

CHB (n = 42)

LC (n = 49)

HCC (n = 102)

HCC with LC (n = 25)

Age (years)

36 [18–57]

39 [20–69]

57 [27–79]

54.5 [26–81]

60 [40–75]

Gender (M/F)

35/13

33/9

41/8

102/0

25/0

WBC* 109/L

6.7 [4.8–11]

5.99 [4.8–11.8]

5.6 [3.2–18]

6 [2.7–17]

5.6 [3–8.4]

RBC* 1012/L

5 [3.8–47]

4.8 [3.8–11.6]

4.2 [2.5–5.7]

4.5 [2.43–6]

4 [3–5.2]

PLT* 109/L

227 [117–376]

217 [117–332]

98 [3.7–320]

166 [40–382]

142 [35–226]

ALT* (IU/L)

23 [8–74]

47 [13–750]

57 [13–395]

42 [12–805]

46 [11–290]

AST* (IU/L)

25 [12–35]

38 [19–599]

84 [15–329]

54.5 [17–670]

116 [25–655]

Total bilirubin* (mg/dl)

13 [6.7–32]

16 [8–32]

29 [9–571]

18 [8–184]

27 [9.6–185]

Direct bilirubin* (mg/dl)

3.5 [1–8]

5.7 [1.4–26]

10 [0.4–291]

6 [1–80]

12.5 [2–59]

Albumin* (g/L)

42 [38–48]

43 [12–48]

30 [3.3–47]

38 [4–47]

32 [22–42]

Prothrombin* (% of standard)

92 [78–127]

94 [72–127]

65 [23.4–92]

78 [19.6–128]

69 [36–124]

HBV viral load* (copies/ml)

6.65×104

5.53×105

8.85×105

5.94×105

4.05×105

[290–6.26×109]

[100–9.9×108]

[203–4.71×108]

[190–2.28×109]

[2040–3.04×109]

Alpha–feto protein (AFP)* (mg/L)

NA

<5

6.8 [1.26–300]

79 [1.38–350]

300 [2.56–300]

Treatments (treated/not-treated)

   

61/41

15/10

TOCE

NA

NA

NA

48/55

11/14

RFA

NA

NA

NA

18/85

8/17

Alcohol injection

NA

NA

NA

26/77

10/15

Surgery

NA

NA

NA

6/97

0/25

  1. ASYM, asymptomatic; CHB, chronic hepatitis B; LC, liver cirrhosis; HCC, hepatocellular carcinoma; WBC, white blood cells; RBC, red blood cells; PLT, platelets; AST and ALT, aspartate and alanine amino transferase; IU, international units; TOCE, transcatheter oily chemoembolization; RFA, radiofrequency ablation; NA, not applicable. Values given are medians and range; (*) P < 0.05 for comparison with all other groups.