Table 3 Performance of Real time PCR while using Liquid culture as the reference standard
Baseline | ||||
|---|---|---|---|---|
MTB | M. avium | |||
Estimate | 95% CI | Estimate | 95% CI | |
Sensitivity (%) | 100 | 96–100 | 100 | 19–100 |
Specificity (%) | 99 | 96–99 | 95 | 91–97 |
Prevalence (%) | 39 | 33–45 | 0.8 | 0.1–2.9 |
PPV (%) | 98 | 94–99 | 15 | 2–45 |
NPV (%) | 100 | 97–100 | 100 | 98–100 |
Likelihood (+) | 144 | 20–1018 | 21 | 12–38 |
Likelihood (−) | 0.00 | - | 0.00 | - |
Kappa stat | 0.9 | 0.9–1.0 | 0.3 | -0.03–0.5 |